18450602

Source:http://linkedlifedata.com/resource/pubmed/id/18450602

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0023467, umls-concept:C0026882, umls-concept:C0085415, umls-concept:C0205307
pubmed:issue	18
pubmed:dateCreated	2008-5-2
pubmed:abstractText	Mutations occur in several genes in cytogenetically normal acute myeloid leukemia (AML) cells: the nucleophosmin gene (NPM1), the fms-related tyrosine kinase 3 gene (FLT3), the CCAAT/enhancer binding protein alpha gene (CEPBA), the myeloid-lymphoid or mixed-lineage leukemia gene (MLL), and the neuroblastoma RAS viral oncogene homolog (NRAS). We evaluated the associations of these mutations with clinical outcomes in patients.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/18450602-18450608, http://linkedlifedata.com/resource/pubmed/commentcorrection/18450602-18687649, http://linkedlifedata.com/resource/pubmed/commentcorrection/18450602-18697246, http://linkedlifedata.com/resource/pubmed/commentcorrection/18450602-18697247, http://linkedlifedata.com/resource/pubmed/commentcorrection/18450602-18697248
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0255562
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/CCAAT-Enhancer-Binding Protein-alpha, http://linkedlifedata.com/resource/pubmed/chemical/Genetic Markers, http://linkedlifedata.com/resource/pubmed/chemical/Myeloid-Lymphoid Leukemia Protein, http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Oncogene Proteins, Viral, http://linkedlifedata.com/resource/pubmed/chemical/fms-Like Tyrosine Kinase 3, http://linkedlifedata.com/resource/pubmed/chemical/nucleophosmin
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	1533-4406
pubmed:author	pubmed-author:BennerAxelA, pubmed-author:BullingerLarsL, pubmed-author:CorbaciogluAndreaA, pubmed-author:DöhnerHartmutH, pubmed-author:DöhnerKonstanzeK, pubmed-author:FröhlingStefanS, pubmed-author:GanserArnoldA, pubmed-author:German-Austrian Acute Myeloid Leukemia Study Group, pubmed-author:HabdankMarianneM, pubmed-author:HeilGerhardG, pubmed-author:KrauterJürgenJ, pubmed-author:MorganMichaelM, pubmed-author:SchlegelbergerBrigitteB, pubmed-author:SchlenkRichard FRF, pubmed-author:SpäthDanielaD
pubmed:copyrightInfo	Copyright 2008 Massachusetts Medical Society.
pubmed:issnType	Electronic
pubmed:day	1
pubmed:volume	358
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1909-18
pubmed:dateRevised	2010-11-18
pubmed:meshHeading	pubmed-meshheading:18450602-Adolescent, pubmed-meshheading:18450602-Adult, pubmed-meshheading:18450602-CCAAT-Enhancer-Binding Protein-alpha, pubmed-meshheading:18450602-Female, pubmed-meshheading:18450602-Genetic Markers, pubmed-meshheading:18450602-Genotype, pubmed-meshheading:18450602-Humans, pubmed-meshheading:18450602-Kaplan-Meier Estimate, pubmed-meshheading:18450602-Leukemia, Myeloid, Acute, pubmed-meshheading:18450602-Male, pubmed-meshheading:18450602-Middle Aged, pubmed-meshheading:18450602-Mutation, pubmed-meshheading:18450602-Myeloid-Lymphoid Leukemia Protein, pubmed-meshheading:18450602-Nuclear Proteins, pubmed-meshheading:18450602-Oncogene Proteins, Viral, pubmed-meshheading:18450602-Remission Induction, pubmed-meshheading:18450602-Stem Cell Transplantation, pubmed-meshheading:18450602-Treatment Outcome, pubmed-meshheading:18450602-fms-Like Tyrosine Kinase 3
pubmed:year	2008
pubmed:articleTitle	Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.
pubmed:affiliation	University Hospital of Ulm, Ulm, Germany.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Evaluation Studies