Linked Life Data

18439224

Source:http://linkedlifedata.com/resource/pubmed/id/18439224

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-4-28
pubmed:abstractText
Experimental studies suggest a role of G protein-mediated signaling pathways in epileptogenesis. A genetic variation affecting the G protein subunit Gbeta3 denoted the C825T polymorphism has been reported to increase the signaling efficiency through G(i) proteins and to modify responses to certain drugs. The C825T polymorphism has also been associated with several diseases including hypertension, diabetes type II, obesity, and major depressive disorder. In this study, we have explored whether the G protein polymorphism C825T is associated with or influences temporal lobe epilepsy (TLE).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0065-1427
pubmed:author
pubmed:issnType
Print
pubmed:volume
188
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
62-6
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
G protein beta3 subunit C825T polymorphism modifies the presentation of temporal lobe epilepsy.
pubmed:affiliation
Department of Neurology, Division of Clinical Neuroscience, Rikshospitalet University Hospital, Oslo, Norway. silje.osberg@gmail.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't