rdf:type |
|
lifeskim:mentions |
umls-concept:C0003320,
umls-concept:C0004358,
umls-concept:C0024141,
umls-concept:C0030705,
umls-concept:C0033105,
umls-concept:C0033684,
umls-concept:C0035435,
umls-concept:C0036421,
umls-concept:C0038856,
umls-concept:C0039194,
umls-concept:C0040711,
umls-concept:C0205210,
umls-concept:C0205217,
umls-concept:C1707520,
umls-concept:C2348519
|
pubmed:issue |
5
|
pubmed:dateCreated |
2008-5-27
|
pubmed:abstractText |
T cell intracytoplasmic antigen 1 (TIA-1) and TIA-1-related protein (TIAR) are involved in posttranscriptional regulation of the expression of tumor necrosis factor alpha (TNFalpha) and other proteins. Given the pivotal role of TNFalpha in chronic inflammatory diseases, this study was undertaken to analyze sera from patients with systemic autoimmune diseases for the presence of autoantibodies to TIA proteins and to investigate the expression of these proteins in inflamed tissue.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0004-3591
|
pubmed:author |
pubmed-author:AringerMartinM,
pubmed-author:GuiducciSerenaS,
pubmed-author:HoeflerElisabethE,
pubmed-author:Jimenez-BojEstherE,
pubmed-author:KarlhoferFranz MFM,
pubmed-author:KedershaNancyN,
pubmed-author:Matucci-CerinicMarcoM,
pubmed-author:SchettGeorgG,
pubmed-author:SmolenJosef SJS,
pubmed-author:SteinerGünterG,
pubmed-author:StummvollGeorgG,
pubmed-author:Tohidast-AkradMakiyehM,
pubmed-author:WalterUlrichU,
pubmed-author:ZimmermannChristofC
|
pubmed:issnType |
Print
|
pubmed:volume |
58
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1226-36
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
|
pubmed:year |
2008
|
pubmed:articleTitle |
Autoantibodies to the translational suppressors T cell intracytoplasmic antigen 1 and T cell intracytoplasmic antigen 1-related protein in patients with rheumatic diseases: increased prevalence in systemic lupus erythematosus and systemic sclerosis and correlation with clinical features.
|
pubmed:affiliation |
Technical University Dresden, Dresden, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|