Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-4-28
pubmed:abstractText
The purposes of this study were to evaluate the effectiveness of 2% chlorhexidine (CHX) gluconate gel, calcium hydroxide [Ca(OH)2] and their combination with iodoform and zinc oxide powder as intracanal medications against select microorganisms, and to measure the pH changes caused by these medications. Antimicrobial activity was determined by the agar diffusion method. The zones of growth inhibition were measured and the results were analyzed statistically by Kruskal-Wallis test (p<0.05). The pH of the pastes was measured right after preparation, after 24 h and 1 week later. The largest mean zones of microbial inhibition were produced by 2% CHX gel, followed by Ca(OH)2 + 2% CHX gel + iodoform, Ca(OH)2 + 2% CHX gel, Ca(OH)2 + 2% CHX gel + zinc oxide, and Ca(OH)2 + water. The mean pH of all medications stayed above 12.0 during the whole experiment, except for CHX gel (pH=7.0). The results of this study showed that all medications had antimicrobial activity, but the most effective against the tested microorganisms were 2% CHX gel, followed by its combination with Ca(OH)2 and iodoform.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1806-4760
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
28-33
pubmed:meshHeading
pubmed-meshheading:18438556-Anti-Infective Agents, Local, pubmed-meshheading:18438556-Calcium Hydroxide, pubmed-meshheading:18438556-Candida albicans, pubmed-meshheading:18438556-Chlorhexidine, pubmed-meshheading:18438556-Colony Count, Microbial, pubmed-meshheading:18438556-Dental Materials, pubmed-meshheading:18438556-Drug Combinations, pubmed-meshheading:18438556-Enterococcus faecalis, pubmed-meshheading:18438556-Humans, pubmed-meshheading:18438556-Hydrocarbons, Iodinated, pubmed-meshheading:18438556-Hydrogen-Ion Concentration, pubmed-meshheading:18438556-Porphyromonas gingivalis, pubmed-meshheading:18438556-Prevotella intermedia, pubmed-meshheading:18438556-Root Canal Irrigants, pubmed-meshheading:18438556-Spectrophotometry, pubmed-meshheading:18438556-Streptococcus mutans, pubmed-meshheading:18438556-Streptococcus sanguis, pubmed-meshheading:18438556-Streptococcus sobrinus, pubmed-meshheading:18438556-Time Factors, pubmed-meshheading:18438556-Zinc Oxide
pubmed:year
2008
pubmed:articleTitle
Antimicrobial effect and pH of chlorhexidine gel and calcium hydroxide alone and associated with other materials.
pubmed:affiliation
Endodontic Area, Department of Restorative Dentistry, School of Dentistry of Piracicaba, State University of Campinas, Piracicaba, SP, Brazil.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't