Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2008-5-29
pubmed:abstractText
We carried out a genome-wide association study of breast cancer predisposition with replication and refinement studies involving 6,145 cases and 33,016 controls and identified two SNPs (rs4415084 and rs10941679) on 5p12 that confer risk, preferentially for estrogen receptor (ER)-positive tumors (OR = 1.27, P = 2.5 x 10(-12) for rs10941679). The nearest gene, MRPS30, was previously implicated in apoptosis, ER-positive tumors and favorable prognosis. A recently reported signal in FGFR2 was also found to associate specifically with ER-positive breast cancer.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1546-1718
pubmed:author
pubmed-author:AbenKatja KKK, pubmed-author:AdebamowoClementC, pubmed-author:AlexiusdottirKristinK, pubmed-author:AndresRaquelR, pubmed-author:BergthorssonJon TJT, pubmed-author:FackenthalJames DJD, pubmed-author:GodinoJavierJ, pubmed-author:GrimssonHlynur NielsHN, pubmed-author:GudjonssonSigurjon ASA, pubmed-author:GudmundssonJuliusJ, pubmed-author:GudmundssonLarusL, pubmed-author:GulcherJeffrey RJR, pubmed-author:HaimanChristopher ACA, pubmed-author:HendersonBrian EBE, pubmed-author:HrafnkelssonJonJ, pubmed-author:JakobsdottirMargretM, pubmed-author:JohannssonJakobJ, pubmed-author:JohannssonOskar TOT, pubmed-author:JonsdottirThoraT, pubmed-author:JonssonGudbjörn FGF, pubmed-author:JonssonThorvaldurT, pubmed-author:KiemeneyLambertus ALA, pubmed-author:KolonelLaurence NLN, pubmed-author:KongAugustineA, pubmed-author:KosticJelenaJ, pubmed-author:KristjanssonKristleifurK, pubmed-author:LambeaJulioJ, pubmed-author:Le MarchandLoicL, pubmed-author:LindblomAnnikaA, pubmed-author:ManolescuAndreiA, pubmed-author:MargolinSaraS, pubmed-author:MassonGisliG, pubmed-author:MayordomoJose IJI, pubmed-author:MillastreEstherE, pubmed-author:MyrdalGardarG, pubmed-author:OgundiranTemidayoT, pubmed-author:OlopadeOlufunmilayo IOI, pubmed-author:PicelliSimoneS, pubmed-author:PoloEduardoE, pubmed-author:RafnarThorunnT, pubmed-author:RantalaJohannaJ, pubmed-author:SaemundsdottirJonaJ, pubmed-author:SaezBertaB, pubmed-author:SigurdssonAsgeirA, pubmed-author:SigurdssonHelgiH, pubmed-author:StaceySimon NSN, pubmed-author:StefanssonKariK, pubmed-author:StrobbeLuc JLJ, pubmed-author:SulemPatrickP, pubmed-author:SveinsdottirSteinunn GSG, pubmed-author:SveinssonThorarinnT, pubmed-author:SwinkelsDorine WDW, pubmed-author:ThorlaciusSteinunnS, pubmed-author:ThorsteinsdottirUnnurU, pubmed-author:TresAlejandroA, pubmed-author:van EngelenburgK C AntonKC
pubmed:issnType
Electronic
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
703-6
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
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