rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2008-6-3
|
pubmed:abstractText |
Exercise ameliorates oxidative stress-mediated diabetic vascular endothelial dysfunction through poorly defined mechanisms. We hypothesised that, in addition to improving metabolic parameters, upregulation of antioxidants such as superoxide dismutase (SOD) mediates exercise-induced reductions of oxidative stress and increased nitric oxide (NO) bioavailability, and also restores vasodilatation.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0012-186X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
51
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1327-37
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:18437348-Adipose Tissue,
pubmed-meshheading:18437348-Animals,
pubmed-meshheading:18437348-Antioxidants,
pubmed-meshheading:18437348-Aorta,
pubmed-meshheading:18437348-Body Weight,
pubmed-meshheading:18437348-Diabetes Mellitus, Type 2,
pubmed-meshheading:18437348-Diabetic Angiopathies,
pubmed-meshheading:18437348-Endothelial Cells,
pubmed-meshheading:18437348-Hyperglycemia,
pubmed-meshheading:18437348-Isometric Contraction,
pubmed-meshheading:18437348-Lipids,
pubmed-meshheading:18437348-Male,
pubmed-meshheading:18437348-Mice,
pubmed-meshheading:18437348-Mice, Mutant Strains,
pubmed-meshheading:18437348-Nitric Oxide,
pubmed-meshheading:18437348-Nitric Oxide Synthase Type II,
pubmed-meshheading:18437348-Nitric Oxide Synthase Type III,
pubmed-meshheading:18437348-Nitrites,
pubmed-meshheading:18437348-Oxidative Stress,
pubmed-meshheading:18437348-Physical Conditioning, Animal,
pubmed-meshheading:18437348-Superoxide Dismutase,
pubmed-meshheading:18437348-Weight Loss
|
pubmed:year |
2008
|
pubmed:articleTitle |
Exercise restores endothelial function independently of weight loss or hyperglycaemic status in db/db mice.
|
pubmed:affiliation |
Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|