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pubmed-article:18437231pubmed:abstractTextPatients with fulminant type 1 diabetes almost completely lack C-peptide even soon after the onset of the disease, and the deficiency continues for the rest of their life. Thus, fulminant type 1 diabetes could serve as a good model of nature to explore the physiological role of C-peptide. For example, patients with fulminant type 1 diabetes have diabetic chronic complications more frequently than those with classical autoimmune type 1 diabetes 5 years after the onset of diabetes, and the higher prevalence could be partly attributable to the complete lack of C-peptide in fulminant type 1 diabetes.lld:pubmed
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pubmed-article:18437231pubmed:dateRevised2011-11-17lld:pubmed
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pubmed-article:18437231pubmed:articleTitleFulminant type 1 diabetes as a model of nature to explore the role of C-peptide.lld:pubmed
pubmed-article:18437231pubmed:affiliationFirst Department of Internal Medicine, Osaka Medical College, 2-7 Daigaku-Machi, Takatsuki 569-8686, Japan.lld:pubmed
pubmed-article:18437231pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:18437231pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed