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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1993-3-15
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pubmed:abstractText |
Weight loss in cancer can be attributed to anorexia and/or increased energy expenditure. In order to understand the contribution of these variables, 36 Wistar rats fed regular diet were randomly distributed in 3 groups: T (12) bearing Walker 256 carcinosarcoma; PF (12) pair fed with T group and C (12) as control group; another group--D (12)--in which rats were fed with low protein (1%) diet. Caloric intake, body and tumor weight were measured daily. Indirect calorimetry was done sequentially each 4 days. After 2 weeks of tumor growth there was significant reduction of caloric intake and carcass weight in T group compared to those of C group. There was no difference in carcass weight between T and PF group. After 3 weeks it was significantly reduced in T group (55.7 Kcal/m2/h against 75.0 of N and 65.1 of PF group). Walker 256 carcinosarcoma is an hypometabolic tumor and the host weight loss associated to its development is due to anorexia.
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pubmed:language |
por
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0041-8781
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
207-14
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1843722-Animals,
pubmed-meshheading:1843722-Body Weight,
pubmed-meshheading:1843722-Calorimetry, Indirect,
pubmed-meshheading:1843722-Carcinoma 256, Walker,
pubmed-meshheading:1843722-Dietary Proteins,
pubmed-meshheading:1843722-Energy Metabolism,
pubmed-meshheading:1843722-Male,
pubmed-meshheading:1843722-Protein-Energy Malnutrition,
pubmed-meshheading:1843722-Rats,
pubmed-meshheading:1843722-Rats, Wistar,
pubmed-meshheading:1843722-Weight Loss
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pubmed:articleTitle |
[Energy metabolism and experimental malignant tumor development].
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pubmed:affiliation |
Laboratório de Metabologia Cirúrgica, Faculdade de Medicina da Universidade de S. Paulo.
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pubmed:publicationType |
Journal Article,
English Abstract
|