To prospectively evaluate an automated volume of interest (VOI)-fitting algorithm for quantitative computed tomography (CT) of proximal femur specimens, correlate bone mineral density (BMD) with biomechanically determined bone strength in vitro, and compare that correlation with those observed at dual-energy x-ray absorptiometry (DXA) measurement of BMD.
Proximal femur specimens: automated 3D trabecular bone mineral density analysis at multidetector CT--correlation with biomechanical strength measurement.
Musculoskeletal and Quantitative Imaging Research, Department of Radiology, University of California, San Francisco, 185 Berry St, Suite 350, San Francisco, CA 94107, USA. mbh@radiology.ucsf.edu