Source:http://linkedlifedata.com/resource/pubmed/id/18429502
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2008-4-23
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pubmed:abstractText |
The aim of this study was to compare the results of an intradermal skin test (IDST) with those of an allergen-specific IgE-ELISA in 210 dogs with atopic dermatitis. All the dogs had a clinical diagnosis of atopic dermatitis and underwent an IDST. The sera of all dogs were analysed for allergen-specific IgE by ELISA using the monoclonal antibody D9 against dog IgE. IDST was used as the standard assay. In both methods, the following antigens provided a positive test result: Dermatophagoides farinae, Acarus siro, Tyrophagus putrescentiae, ragweed, mugwort and Lepidoglyphus destructor. ELISA had an overall sensitivity of 82.4% and an overall specificity of 93.8%. The overall accuracy of the ELISA was 91.3%. The evaluated monoclonal D9 ELISA was found to be a reliable tool for the diagnosis of those allergens that cause clinical atopy, and can be recommended for use in dogs when immunotherapy is a therapeutic option.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0036-7281
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
150
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
117-22
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pubmed:meshHeading |
pubmed-meshheading:18429502-Animals,
pubmed-meshheading:18429502-Antibodies, Monoclonal,
pubmed-meshheading:18429502-Dermatitis, Atopic,
pubmed-meshheading:18429502-Dog Diseases,
pubmed-meshheading:18429502-Dogs,
pubmed-meshheading:18429502-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:18429502-Female,
pubmed-meshheading:18429502-Immunoglobulin E,
pubmed-meshheading:18429502-Intradermal Tests,
pubmed-meshheading:18429502-Male,
pubmed-meshheading:18429502-Sensitivity and Specificity
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pubmed:year |
2008
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pubmed:articleTitle |
Comparison between an intradermal skin test and allergen-specific IgE-ELISA for canine atopic dermatitis.
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pubmed:affiliation |
Department and Clinic of Internal Medicine, Faculty of Veterinary Science, Szent István University, Hungary.
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pubmed:publicationType |
Journal Article
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