Linked Life Data

18428858

Source:http://linkedlifedata.com/resource/pubmed/id/18428858

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-4-22
pubmed:abstractText
Small circular oligonucleotides can be used for diagnostic, therapeutic, and laboratory purposes. These systems have gained considerable attention in recent years because they form unusually strong and specific complexes with RNA and DNA strands. Synthetic circular DNAs of 20 to 200 nucleotides can also serve as catalysts for amplified DNA and RNA synthesis by a rolling circle mechanism. This unit presents methods for synthesizing small circular oligonucleotides. These simple "one-pot" procedures are carried out using short DNA splints that hold the circle together until it is chemically or enzymatically ligated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1934-9289
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
Chapter 5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
Unit 5.2
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Chemical and enzymatic methods for preparing circular single-stranded DNAs.
pubmed:affiliation
University of Rochester, Rochester, New York, USA.
pubmed:publicationType
Journal Article