Linked Life Data

1842872

Source:http://linkedlifedata.com/resource/pubmed/id/1842872

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1993-1-27
pubmed:abstractText
When tonsillar B cells were cultured in the presence of exogenous interleukin-6 (IL-6), a small portion of them differentiated into plasma cells which seemed to have IL-6 receptors on their surfaces. The number of plasma cells tended to be greater in the tonsils of children than in the tonsils of adults. When tonsillar cells collected by Ficoll-Conray's method were cultured in medium containing IL-6, T cells differentiated and the number of activated T cells increased. Of the four subsets of T cells, this effect of IL-6 was strongest on cytotoxic T cells. IL-6-mediated proliferation and activation of cytotoxic T cells tended to be greater in the tonsils of children than in those of adults. IL-6 is produced in some tonsillar macrophages. The number of macrophages producing IL-6 was very different in different subjects. However, the number of macrophages producing IL-6 in tonsils of children tended to be greater than the number in tonsils of adults.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0365-5237
pubmed:author
pubmed:issnType
Print
pubmed:volume
486
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
245-53
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Influence of IL-6 on proliferation and differentiation of tonsillar lymphocytes and detection of IL-6 producing cells in tonsil.
pubmed:affiliation
Department of Otorhinolaryngology, Osaka Municipal Shirokita Citizen's Hospital, Japan.
pubmed:publicationType
Journal Article