Linked Life Data

1842867

Source:http://linkedlifedata.com/resource/pubmed/id/1842867

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1993-1-27
pubmed:abstractText
Nasal mucosa is a subject of surgical operation for patients with nasal disorders. However, our knowledge about the regeneration of nasal mucosa after such a mechanical injury is still limited. In this study we investigated the recovery or regenerative process of nasal mucosa in rabbits after mechanical injury on the basis of ultrastructural as well as functional observations. Complete recovery of nasal mucosa was obtained in 5 days if the basal cells and basement membrane were intact. When the total layer of nasal mucosa was injured mechanically, regenerative stratified epithelium covered the defect in 1 week, new ciliated cells appeared in 3 weeks, and complete regeneration was observed at 6 weeks. At 3 weeks when the first appearance of cilia was observed, the beating activity of the cilia was in the normal range. In conclusion, we observed a great regeneration ability following mechanical injury in the nasal mucosa. The process of regeneration in the nasal mucosa after mechanical injury appears to depend on whether the basal cells and basement membrane are intact or not.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0365-5237
pubmed:author
pubmed:issnType
Print
pubmed:volume
486
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
193-201
pubmed:dateRevised
2008-2-13
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Regeneration of nasal mucosa following mechanical injury.
pubmed:affiliation
Department of Otolaryngology, Osaka City University Medical School, Japan.
pubmed:publicationType
Journal Article