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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-4-28
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pubmed:abstractText |
This study assessed the association of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection with non-Hodgkin's lymphoma in a highly HBV-endemic area. The prevalence of either HBV or HCV infection in 235 patients with non-Hodgkin's lymphoma was compared with that of an age- and sex-matched hospital control group of 235 patients. The prevalence of HBV infection was higher in B-cell non-Hodgkin's lymphoma (15.5%) than control (8.1%), but the prevalence of HCV infection in the non-Hodgkin's lymphoma patients (2.1%) and control group (3%) was similar. HBV prevalence increased significantly with age in the B-cell non-Hodgkin's lymphoma patients. The presence of HBV proteins and DNA in lymphoma tissues and peripheral blood mononuclear cells (PBMCs) from HBV-infected non-Hodgkin's lymphoma patients was also investigated using immunohistochemistry and PCR. HBV DNA was frequently detected in PBMCs from HBV-infected non-Hodgkin's lymphoma patients, but HBV antigens were not. Therefore, HBV infection, but not HCV infection, was associated with B-cell non-Hodgkin's lymphoma in Korea, suggesting a possible role for HBV in the development of non-Hodgkin's lymphoma.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0146-6615
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pubmed:author |
pubmed-author:ChangYoon HwanYH,
pubmed-author:ChoJang HyunJH,
pubmed-author:ChoiKui SungKS,
pubmed-author:HanChul JuCJ,
pubmed-author:JeongSook-HyangSH,
pubmed-author:JungHa HyunHH,
pubmed-author:KayL WLW,
pubmed-author:KiSeung SeogSS,
pubmed-author:KimYou CheoulYC,
pubmed-author:LeeKee HoKH,
pubmed-author:LeeMyoungjinM,
pubmed-author:LeeSeung SookSS,
pubmed-author:ParkSu CheolSC,
pubmed-author:ParkYeon HeeYH
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pubmed:issnType |
Print
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
960-6
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pubmed:meshHeading |
pubmed-meshheading:18428141-Adolescent,
pubmed-meshheading:18428141-Adult,
pubmed-meshheading:18428141-Aged,
pubmed-meshheading:18428141-Aged, 80 and over,
pubmed-meshheading:18428141-Child,
pubmed-meshheading:18428141-Child, Preschool,
pubmed-meshheading:18428141-DNA, Viral,
pubmed-meshheading:18428141-Female,
pubmed-meshheading:18428141-Genes, Viral,
pubmed-meshheading:18428141-Hepatitis B,
pubmed-meshheading:18428141-Hepatitis B Core Antigens,
pubmed-meshheading:18428141-Hepatitis B Surface Antigens,
pubmed-meshheading:18428141-Hepatitis B virus,
pubmed-meshheading:18428141-Hepatitis C,
pubmed-meshheading:18428141-Humans,
pubmed-meshheading:18428141-Immunohistochemistry,
pubmed-meshheading:18428141-Korea,
pubmed-meshheading:18428141-Leukocytes, Mononuclear,
pubmed-meshheading:18428141-Lymphoma, B-Cell,
pubmed-meshheading:18428141-Lymphoma, Non-Hodgkin,
pubmed-meshheading:18428141-Male,
pubmed-meshheading:18428141-Middle Aged,
pubmed-meshheading:18428141-Prevalence,
pubmed-meshheading:18428141-Stomach Neoplasms
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pubmed:year |
2008
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pubmed:articleTitle |
High prevalence of hepatitis B virus infection in patients with B-cell non-Hodgkin's lymphoma in Korea.
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pubmed:affiliation |
Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Science, Seoul, South Korea.
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pubmed:publicationType |
Journal Article
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