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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-6-25
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pubmed:abstractText |
Mycophenolic acid (MPA) is used clinically to prevent graft rejection but may increase the risk of fungal infection. We observed that MPA enhanced the Aspergillus fumigatus-induced oxidative burst of polymorphonuclear neutrophils, but without a corresponding increase in fungal killing. Furthermore, MPA inhibited the proinflammatory cytokine response and maturation of dendritic cells.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-10878285,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-12358925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-12394169,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-12765994,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-12974756,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-14704765,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-15067076,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-15585866,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-16051207,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-16357277,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-16539644,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-16797370,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426895-8680053
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1098-6596
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2644-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18426895-Aspergillus fumigatus,
pubmed-meshheading:18426895-Cell Differentiation,
pubmed-meshheading:18426895-Cytokines,
pubmed-meshheading:18426895-Dendritic Cells,
pubmed-meshheading:18426895-Graft Rejection,
pubmed-meshheading:18426895-Humans,
pubmed-meshheading:18426895-Immunosuppressive Agents,
pubmed-meshheading:18426895-Inflammation Mediators,
pubmed-meshheading:18426895-Mycophenolic Acid,
pubmed-meshheading:18426895-Neutrophils,
pubmed-meshheading:18426895-Respiratory Burst
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pubmed:year |
2008
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pubmed:articleTitle |
Impact of mycophenolic acid on the functionality of human polymorphonuclear neutrophils and dendritic cells during interaction with Aspergillus fumigatus.
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pubmed:affiliation |
Medizinische Klinik II, Universität Würzburg, 97070 Würzburg, Germany.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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