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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-6-30
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pubmed:abstractText |
A recent meta-analysis demonstrated a nominal association of the ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) K-->Q missense single nucleotide polymorphism (SNP) at position 121 with type 2 diabetes. We set out to confirm the association of ENPP1 K121Q with hyperglycemia, expand this association to insulin resistance traits, and determine whether the association stems from K121Q or another variant in linkage disequilibrium with it.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-10480624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-10615944,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-10741566,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-11289049,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-14671192,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-15793263,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-16186408,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-16865358,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-16936213,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-16968801,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-17065358,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-17065359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-17143316,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-17228024,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-17460697,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-17463246,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-17463248,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-17463249,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-17563456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-17704904,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-18071025,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-18199690,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-3899825,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-7830796,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-9084965,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-9518396,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/18426862-9648833
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1939-327X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1971-7
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pubmed:dateRevised |
2011-8-1
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pubmed:meshHeading |
pubmed-meshheading:18426862-Amino Acid Substitution,
pubmed-meshheading:18426862-Blood Glucose,
pubmed-meshheading:18426862-Cardiovascular Diseases,
pubmed-meshheading:18426862-Diabetes Mellitus, Type 2,
pubmed-meshheading:18426862-European Continental Ancestry Group,
pubmed-meshheading:18426862-Female,
pubmed-meshheading:18426862-Genetic Variation,
pubmed-meshheading:18426862-Humans,
pubmed-meshheading:18426862-Hyperglycemia,
pubmed-meshheading:18426862-Insulin Resistance,
pubmed-meshheading:18426862-Linkage Disequilibrium,
pubmed-meshheading:18426862-Male,
pubmed-meshheading:18426862-Massachusetts,
pubmed-meshheading:18426862-Middle Aged,
pubmed-meshheading:18426862-Mutation, Missense,
pubmed-meshheading:18426862-Phosphoric Diester Hydrolases,
pubmed-meshheading:18426862-Polymorphism, Single Nucleotide,
pubmed-meshheading:18426862-Pyrophosphatases,
pubmed-meshheading:18426862-Quantitative Trait Loci,
pubmed-meshheading:18426862-Risk Factors
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pubmed:year |
2008
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pubmed:articleTitle |
Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study.
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pubmed:affiliation |
Center for Human Genetic Research and Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
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pubmed:publicationType |
Journal Article,
Multicenter Study,
Research Support, N.I.H., Extramural
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