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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-4-22
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pubmed:abstractText |
Endothelial nitric oxide synthase (eNOS) intron 4a/b polymorphism is associated with plasma NO concentrations and coronary artery disease/hypertension in various populations. GH deficiency in adulthood predisposes to reduced NO concentrations and premature atherosclerosis. Our aim was to determine whether intron 4a/b polymorphism of eNOS gene influences endothelial function and early atherosclerotic changes in GH-deficient hypopituitary patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1479-683X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
158
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
615-22
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pubmed:meshHeading |
pubmed-meshheading:18426819-Adult,
pubmed-meshheading:18426819-Atherosclerosis,
pubmed-meshheading:18426819-Case-Control Studies,
pubmed-meshheading:18426819-Cholesterol, LDL,
pubmed-meshheading:18426819-Cross-Sectional Studies,
pubmed-meshheading:18426819-Female,
pubmed-meshheading:18426819-Genotype,
pubmed-meshheading:18426819-Growth Hormone,
pubmed-meshheading:18426819-Humans,
pubmed-meshheading:18426819-Hypopituitarism,
pubmed-meshheading:18426819-Insulin-Like Growth Factor I,
pubmed-meshheading:18426819-Introns,
pubmed-meshheading:18426819-Male,
pubmed-meshheading:18426819-Middle Aged,
pubmed-meshheading:18426819-Nitric Oxide Synthase Type III,
pubmed-meshheading:18426819-Polymorphism, Genetic
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pubmed:year |
2008
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pubmed:articleTitle |
Endothelial nitric oxide synthase intron 4a/b polymorphism and early atherosclerotic changes in hypopituitary GH-deficient adult patients.
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pubmed:affiliation |
Division of Endocrinology, Department of Medicine, Istanbul Faculty of Medicine, Istanbul University, 34390 Capa, Istanbul, Turkey.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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