rdf:type |
|
lifeskim:mentions |
umls-concept:C0008976,
umls-concept:C0019004,
umls-concept:C0023779,
umls-concept:C0030705,
umls-concept:C0034656,
umls-concept:C0449258,
umls-concept:C0717537,
umls-concept:C0718050,
umls-concept:C1611184,
umls-concept:C2587213,
umls-concept:C2603343
|
pubmed:issue |
6
|
pubmed:dateCreated |
2008-5-26
|
pubmed:databankReference |
|
pubmed:abstractText |
Previous clinical trials showed that progression of coronary artery calcification (CAC) may be slower in hemodialysis patients treated with sevelamer than those treated with calcium-based phosphate binders. Because sevelamer decreases low-density lipoprotein cholesterol (LDL-C) levels, we hypothesized that intensive lowering of LDL-C levels with atorvastatin in hemodialysis patients treated with calcium acetate would result in CAC progression rates similar to those in sevelamer-treated patients.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1523-6838
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
51
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
952-65
|
pubmed:dateRevised |
2008-11-13
|
pubmed:meshHeading |
pubmed-meshheading:18423809-Acetates,
pubmed-meshheading:18423809-Anticholesteremic Agents,
pubmed-meshheading:18423809-Calcinosis,
pubmed-meshheading:18423809-Calcium Compounds,
pubmed-meshheading:18423809-Chelating Agents,
pubmed-meshheading:18423809-Coronary Artery Disease,
pubmed-meshheading:18423809-Disease Progression,
pubmed-meshheading:18423809-Female,
pubmed-meshheading:18423809-Heptanoic Acids,
pubmed-meshheading:18423809-Humans,
pubmed-meshheading:18423809-Male,
pubmed-meshheading:18423809-Middle Aged,
pubmed-meshheading:18423809-Polyamines,
pubmed-meshheading:18423809-Prospective Studies,
pubmed-meshheading:18423809-Pyrroles,
pubmed-meshheading:18423809-Renal Dialysis,
pubmed-meshheading:18423809-Time Factors
|
pubmed:year |
2008
|
pubmed:articleTitle |
A 1-year randomized trial of calcium acetate versus sevelamer on progression of coronary artery calcification in hemodialysis patients with comparable lipid control: the Calcium Acetate Renagel Evaluation-2 (CARE-2) study.
|
pubmed:affiliation |
Department of Medicine, Division of Nephrology, University of Texas Health Sciences Center, San Antonio, TX 78229-3900, USA. qunibi@uthscsa.edu
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|