Linked Life Data

18422066

Source:http://linkedlifedata.com/resource/pubmed/id/18422066

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6 Pt 2
pubmed:dateCreated
2008-4-21
pubmed:abstractText
BK virus nephropathy may lead to kidney transplant failure. BK infection and acute rejection are clinically undistinguishable, therefore diagnosis of these entities is critical to establish the correct treatment. The new molecular methods using PCR and real time PCR have significantly contributed to the rapid and sensitive diagnosis of BK virus. Furthermore, viral load determination in-plasma has significantly been associated with BK virus nephropathy. Definite diagnosis of nephropathy requires renal biopsy, although due to the multifocal nature of the disease sensitivity may be less than 100%. BK detection in blood and urine by PCR has contributed to the diagnosis of nephropathy in a more standardized and less invasive way. Recently, quantification of BK virus in plasma has been used for the diagnosis and monitoring of this disease. In the present study, we describe the validation of a real time PCR method for BK virus detection in plasma and urine and its application for diagnosis and monitoring in a renal transplant patient with nephropathy.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0025-7680
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
719-22
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
[BK virus nephropathy after renal transplantation. Diagnosis and prognosis by real time PCR].
pubmed:affiliation
Laboratorio de Virología Clínica, Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Buenos Aires, Argentina. mechavarria@cemic.edu.ar
pubmed:publicationType
Journal Article, English Abstract, Case Reports, Validation Studies