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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3-4
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pubmed:dateCreated |
2008-4-18
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pubmed:abstractText |
Diurnal phagocytosis of spent photoreceptor outer segment fragments by the retinal pigment epithelium (RPE) is critical for vision. We recently identified an important role for alphavbeta5 integrin receptors and their ligand Milk fat globule-EGF factor 8 (MFG-E8) in RPE phagocytosis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/Ccl2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Ccr2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Cx3cr1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Integrins,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Mfge8 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Milk Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CCR2,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Chemokine,
http://linkedlifedata.com/resource/pubmed/chemical/integrin alphavbeta8
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0259
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pubmed:author |
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pubmed:copyrightInfo |
2008 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
120-3
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pubmed:meshHeading |
pubmed-meshheading:18421224-Animals,
pubmed-meshheading:18421224-Antigens, Surface,
pubmed-meshheading:18421224-Biological Markers,
pubmed-meshheading:18421224-Chemokine CCL2,
pubmed-meshheading:18421224-Cytokines,
pubmed-meshheading:18421224-Disease Models, Animal,
pubmed-meshheading:18421224-Integrins,
pubmed-meshheading:18421224-Ligands,
pubmed-meshheading:18421224-Macular Degeneration,
pubmed-meshheading:18421224-Mice,
pubmed-meshheading:18421224-Mice, Inbred C57BL,
pubmed-meshheading:18421224-Mice, Knockout,
pubmed-meshheading:18421224-Microscopy, Electron, Transmission,
pubmed-meshheading:18421224-Microscopy, Fluorescence,
pubmed-meshheading:18421224-Milk Proteins,
pubmed-meshheading:18421224-Pigment Epithelium of Eye,
pubmed-meshheading:18421224-Receptors, CCR2,
pubmed-meshheading:18421224-Receptors, Chemokine
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pubmed:year |
2008
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pubmed:articleTitle |
Lack of alphavbeta5 integrin receptor or its ligand MFG-E8: distinct effects on retinal function.
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pubmed:affiliation |
Department of Ophthalmology, Dyson Vision Research Institute, New York, NY 10065, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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