rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-4-18
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pubmed:abstractText |
Antiretroviral therapy (ART)-associated lipoatrophy involves mitochondrial dysfunction. Iron metabolism impacts mitochondrial function and oxidative stress. Mitochondrial haplogroups and hemochromatosis gene (HFE) polymorphisms have been associated with ART-induced neuropathy. We assessed relationships between these variants and lipoatrophy.
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pubmed:grant |
|
pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Mar
|
pubmed:issn |
0022-1899
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pubmed:author |
pubmed-author:AIDS Clinical Trials Group 384 and A5005s Study Teams,
pubmed-author:CanterJeffrey AJA,
pubmed-author:DubéMichaelM,
pubmed-author:GrinspoonStevenS,
pubmed-author:HaasDavid WDW,
pubmed-author:HulganToddT,
pubmed-author:KallianpurAsha RAR,
pubmed-author:MotsingerAlison AAA,
pubmed-author:MulliganKathleenK,
pubmed-author:RobbinsGregory KGK,
pubmed-author:TebasPabloP
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pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
197
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
858-66
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pubmed:dateRevised |
2008-8-13
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pubmed:meshHeading |
pubmed-meshheading:18419350-Absorptiometry, Photon,
pubmed-meshheading:18419350-Adult,
pubmed-meshheading:18419350-Anti-Retroviral Agents,
pubmed-meshheading:18419350-DNA, Mitochondrial,
pubmed-meshheading:18419350-Female,
pubmed-meshheading:18419350-Genotype,
pubmed-meshheading:18419350-HIV Infections,
pubmed-meshheading:18419350-HIV-1,
pubmed-meshheading:18419350-HIV-Associated Lipodystrophy Syndrome,
pubmed-meshheading:18419350-Hemochromatosis,
pubmed-meshheading:18419350-Humans,
pubmed-meshheading:18419350-Male,
pubmed-meshheading:18419350-Middle Aged,
pubmed-meshheading:18419350-Polymorphism, Single Nucleotide
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pubmed:year |
2008
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pubmed:articleTitle |
Hemochromatosis gene polymorphisms, mitochondrial haplogroups, and peripheral lipoatrophy during antiretroviral therapy.
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pubmed:affiliation |
Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA. todd.hulgan@vanderbilt.edu
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Research Support, N.I.H., Extramural
|