Linked Life Data

1841906

Source:http://linkedlifedata.com/resource/pubmed/id/1841906

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1992-12-15
pubmed:abstractText
Metabolic imaging using positron emission tomography (PET) facilitates the identification of ischemic but viable myocardium. In this study, the predictive value of PET for identifying improvement in regional function after coronary artery bypass grafting (CABG) was assessed. PET perfusion and metabolic imagings using N-13 ammonia and F-18 deoxyglucose (FDG) were performed before and 5-7 weeks after CABG in 25 patients with coronary artery disease. Each of the 5 myocardial segments of the left ventricle was categorized as normal, ischemic and infarcted based on the findings of perfusion and PET metabolic images. Among 58 hypoperfused segments, abnormal perfusion in 17 of 25 ischemic segments was correctly predicted to be reversible (68% prediction accuracy), and that in 25 of 33 infarcted segments were correctly predicted to be irreversible (76% prediction accuracy) (p < 0.001). Similarly, among 53 asynergy segments assessed by radionuclide ventriculography, abnormal wall motion in 21 of 27 asynergy segments was correctly predicted to be reversible (78% prediction accuracy), and that in 21 of 26 PET viable segments was correctly predicted to be irreversible (81% prediction accuracy) (p < 0.001). Thus, preoperative metabolic imaging using PET appears to be useful for predicting responses to CABG.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0914-5087
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
193-201
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Prediction of reversible ischemia after coronary artery bypass grafting by positron emission tomography.
pubmed:affiliation
Department of Radiology and Nuclear Medicine, Faculty of Medicine, Kyoto University.
pubmed:publicationType
Journal Article, Clinical Trial