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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2008-4-16
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pubmed:abstractText |
The variant allele of CCND1 G870A encodes a splice variant of the cyclin D1 protein, which possesses an increased half-life. To confirm the phenotypic effect of the variant allele, we examined the immunohistochemical staining pattern of the protein in tumors from a case population of head and neck squamous cell carcinoma (HNSCC) and compared it with the genotype of these individuals. We also examined how this genotype was associated with the risk of HNSCC and if this genotype-phenotype association was related to patient outcome.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-10440744,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-10492624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-10647931,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-11307062,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-11470749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-11861215,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-11981277,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-12097237,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-15695117,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-16023150,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-16638786,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-16763272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-17119046,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-17220338,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-17237035,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-2987361,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-3365707,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-4648515,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-7675441,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-7850812,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-8290586,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-8513492,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-8832554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-9024716,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18413827-9796972
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2371-7
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pubmed:dateRevised |
2010-12-3
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pubmed:meshHeading |
pubmed-meshheading:18413827-Adult,
pubmed-meshheading:18413827-Aged,
pubmed-meshheading:18413827-Carcinoma, Squamous Cell,
pubmed-meshheading:18413827-Cyclin D1,
pubmed-meshheading:18413827-DNA, Viral,
pubmed-meshheading:18413827-Female,
pubmed-meshheading:18413827-Genotype,
pubmed-meshheading:18413827-Head and Neck Neoplasms,
pubmed-meshheading:18413827-Human papillomavirus 16,
pubmed-meshheading:18413827-Humans,
pubmed-meshheading:18413827-Immunohistochemistry,
pubmed-meshheading:18413827-Male,
pubmed-meshheading:18413827-Middle Aged,
pubmed-meshheading:18413827-Phenotype,
pubmed-meshheading:18413827-Risk Factors
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pubmed:year |
2008
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pubmed:articleTitle |
A genotype-phenotype examination of cyclin D1 on risk and outcome of squamous cell carcinoma of the head and neck.
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pubmed:affiliation |
Department of Pathology and Laboratory Medicine, Brown University, Providence, RI 02912, USA. carmen_marsit@brown.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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