rdf:type |
|
lifeskim:mentions |
umls-concept:C0011847,
umls-concept:C0017725,
umls-concept:C0026336,
umls-concept:C0039011,
umls-concept:C0205177,
umls-concept:C0205531,
umls-concept:C0226896,
umls-concept:C0376674,
umls-concept:C0442027,
umls-concept:C0450442,
umls-concept:C0534500,
umls-concept:C0740411,
umls-concept:C1280500,
umls-concept:C1527415,
umls-concept:C2000403
|
pubmed:issue |
5
|
pubmed:dateCreated |
2008-9-1
|
pubmed:abstractText |
This study was conducted to evaluate the suitability of a new minipig model for investigating aspects of diabetes such as delayed gastric emptying and glucose metabolism abnormalities, and to test the effects of mitemcinal (GM-611), an orally active erythromycin-derived motilin receptor agonist, on gastric emptying and postprandial glucose in normal and diabetic minipigs.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1873-460X
|
pubmed:author |
pubmed-author:ArakawaHitoshiH,
pubmed-author:KatagiriKoichiK,
pubmed-author:KierLL,
pubmed-author:MonnaiMakotoM,
pubmed-author:MuramatsuHiroyasuH,
pubmed-author:OdaYasuhiroY,
pubmed-author:OmuraSatoshiS,
pubmed-author:OnomaMitsuM,
pubmed-author:OzakiKen-ichiK,
pubmed-author:TakanashiHisanoriH,
pubmed-author:WatanabeToshihikoT,
pubmed-author:YogoKenjiK
|
pubmed:issnType |
Electronic
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
339-47
|
pubmed:meshHeading |
pubmed-meshheading:18413164-Administration, Oral,
pubmed-meshheading:18413164-Animals,
pubmed-meshheading:18413164-Blood Glucose,
pubmed-meshheading:18413164-Diabetes Mellitus, Experimental,
pubmed-meshheading:18413164-Drug Evaluation, Preclinical,
pubmed-meshheading:18413164-Erythromycin,
pubmed-meshheading:18413164-Gastric Emptying,
pubmed-meshheading:18413164-Gastrointestinal Agents,
pubmed-meshheading:18413164-Gastroparesis,
pubmed-meshheading:18413164-Islets of Langerhans,
pubmed-meshheading:18413164-Kidney,
pubmed-meshheading:18413164-Liver,
pubmed-meshheading:18413164-Male,
pubmed-meshheading:18413164-Postprandial Period,
pubmed-meshheading:18413164-Streptozocin,
pubmed-meshheading:18413164-Swine,
pubmed-meshheading:18413164-Swine, Miniature
|
pubmed:articleTitle |
Effects of mitemcinal (GM-611), an orally active erythromycin-derived prokinetic agent, on delayed gastric emptying and postprandial glucose in a new minipig model of diabetes.
|
pubmed:affiliation |
Fuji-Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd., Gotemba, Shizuoka 412-8513, Japan.
|
pubmed:publicationType |
Journal Article
|