rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2008-5-9
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pubmed:abstractText |
Current literature and our previous results on expression patterns of oocyte-specific genes and transcription factors suggest a global but highly regulated maternal mRNA degradation at the time of embryonic genome activation (EGA). MicroRNAs (miRNAs) are small, non-coding regulatory RNAs (19-23 nucleotides) that regulate gene expression by guiding target mRNA cleavage or translational inhibition. These regulatory RNAs are potentially involved in the degradation of maternally inherited mRNAs during early embryogenesis.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-213X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
41
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18412968-Analysis of Variance,
pubmed-meshheading:18412968-Animals,
pubmed-meshheading:18412968-Cloning, Molecular,
pubmed-meshheading:18412968-Embryo, Nonmammalian,
pubmed-meshheading:18412968-Gene Expression Regulation, Developmental,
pubmed-meshheading:18412968-Genetic Markers,
pubmed-meshheading:18412968-MicroRNAs,
pubmed-meshheading:18412968-Oncorhynchus mykiss,
pubmed-meshheading:18412968-RNA,
pubmed-meshheading:18412968-RNA, Messenger,
pubmed-meshheading:18412968-Sequence Analysis, RNA,
pubmed-meshheading:18412968-Tissue Distribution
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pubmed:year |
2008
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pubmed:articleTitle |
Cloning and characterization of microRNAs from rainbow trout (Oncorhynchus mykiss): their expression during early embryonic development.
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pubmed:affiliation |
Laboratory of Animal Biotechnology and Genomics, Division of Animal and Nutritional Sciences, West Virginia University, Morgantown, WV 26506, USA. raghuveerkr@gmail.com
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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