Linked Life Data

18411724

Source:http://linkedlifedata.com/resource/pubmed/id/18411724

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2008-4-16
pubmed:abstractText
Cells and the extracellular matrix of the loose connective tissue as well as the macrophage system were studied in experimental crush-syndrome in 50 rats using histological, histochemical and electron microscopical methods. The results of the investigation have shown that the components of the loose connective tissue and the macrophage system actively responded to 1-hour-long hindlimb compression. Severe structural and functional injury of the cells and extracellular matrix of the subcutaneous loose connective tissue and of the stroma of different organs (lung, heart, kidney) was detected on dayl, was especially pronounced on day 7 and partly regressed by day 30 after the decompression. These changes included the structural damage of fibroblasts, changes in the number and degranulation of the mast cells, inhibition of RNA synthesis in plasmoblasts and lymphoblasts and the destruction of the collagen, elastic and reticular fibers. The number of macrophages in the liver, lungs, spleen, lymph nodes was reduced on days 1 and 7 after the decompression, in some organs this effect persisted until day 20. The activity of acid phosphatase was reduced in the macrophages in crush-syndrome.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1026-3543
pubmed:author
pubmed:issnType
Print
pubmed:volume
132
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
46-51
pubmed:dateRevised
2011-5-9
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
[Structural and functional changes of the loose connective tissue and macrophage system in experimental crush-syndrome].
pubmed:publicationType
Journal Article, English Abstract