Source:http://linkedlifedata.com/resource/pubmed/id/18409065
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2008-6-4
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pubmed:abstractText |
From the EtOAc-soluble fraction of an MeOH extract of the stems of Tricalysia dubia, two new rearranged ent-kaurane derivatives, named tricalysiolides H and I, were isolated, together with five known rearranged ent-kauranes, i.e. tricalysiolides A-E, stigmast-4-en-6beta-ol-3-one, (+)-pinoresinol, scopoletin and syringaldehyde. Their structures were elucidated from spectroscopic evidence, and their cytotoxicity toward KB cells and P-gp inhibitory activity were assayed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1861-0293
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
314-20
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pubmed:dateRevised |
2009-10-30
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pubmed:meshHeading |
pubmed-meshheading:18409065-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:18409065-Diterpenes, Kaurane,
pubmed-meshheading:18409065-Drug Screening Assays, Antitumor,
pubmed-meshheading:18409065-Flow Cytometry,
pubmed-meshheading:18409065-Humans,
pubmed-meshheading:18409065-K562 Cells,
pubmed-meshheading:18409065-KB Cells,
pubmed-meshheading:18409065-P-Glycoprotein,
pubmed-meshheading:18409065-Plant Extracts,
pubmed-meshheading:18409065-Plant Stems,
pubmed-meshheading:18409065-Rubiaceae,
pubmed-meshheading:18409065-Spectrum Analysis
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pubmed:year |
2008
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pubmed:articleTitle |
Rearranged ent-kauranes from the stems of Tricalysia dubia and their biological activities.
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pubmed:affiliation |
Department of Pharmacognosy, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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