Source:http://linkedlifedata.com/resource/pubmed/id/18408250
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-2-13
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pubmed:abstractText |
Interferon regulatory factor 5 (IRF5) is a member of the IRF family of transcription factors, which regulate the production of proinflammatory cytokines. Polymorphisms in the IRF5 gene have been associated with susceptibility to systemic lupus erythaematosus (SLE) in Caucasian and Asian populations, but their involvement in other autoimmune diseases is still uncertain. Here, we assessed the genetic role of IRF5 in susceptibility to rheumatoid arthritis (RA) in Japanese subjects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1468-2060
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
377-83
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18408250-Arthritis, Rheumatoid,
pubmed-meshheading:18408250-Case-Control Studies,
pubmed-meshheading:18408250-Genetic Predisposition to Disease,
pubmed-meshheading:18408250-Genotype,
pubmed-meshheading:18408250-HLA-DR Antigens,
pubmed-meshheading:18408250-HLA-DRB1 Chains,
pubmed-meshheading:18408250-Humans,
pubmed-meshheading:18408250-Interferon Regulatory Factors,
pubmed-meshheading:18408250-Japan,
pubmed-meshheading:18408250-Linkage Disequilibrium,
pubmed-meshheading:18408250-Polymorphism, Single Nucleotide,
pubmed-meshheading:18408250-Promoter Regions, Genetic
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pubmed:year |
2009
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pubmed:articleTitle |
A single nucleotide polymorphism in the IRF5 promoter region is associated with susceptibility to rheumatoid arthritis in the Japanese population.
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pubmed:affiliation |
Department of Allergy and Rheumatology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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