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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-4-11
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pubmed:abstractText |
Rapid induction of profound hypothermia for emergency preservation and resuscitation can improve survival from uncontrolled lethal hemorrhage in large animal models. We have previously demonstrated that profound hypothermia (10 degrees C) must be induced rapidly (2 degrees C/min) and reversed gradually (0.5 degrees C/min) for best results. However, the maximum duration of hypothermic arrest in a clinically relevant trauma model remains unknown.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1529-8809
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
912-22
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pubmed:meshHeading |
pubmed-meshheading:18404056-Animals,
pubmed-meshheading:18404056-Body Temperature,
pubmed-meshheading:18404056-Brain,
pubmed-meshheading:18404056-Cardiopulmonary Bypass,
pubmed-meshheading:18404056-Circulatory Arrest, Deep Hypothermia Induced,
pubmed-meshheading:18404056-Cognition,
pubmed-meshheading:18404056-Disease Models, Animal,
pubmed-meshheading:18404056-Female,
pubmed-meshheading:18404056-Hemodynamics,
pubmed-meshheading:18404056-Neuropsychological Tests,
pubmed-meshheading:18404056-Probability,
pubmed-meshheading:18404056-Random Allocation,
pubmed-meshheading:18404056-Risk Assessment,
pubmed-meshheading:18404056-Sensitivity and Specificity,
pubmed-meshheading:18404056-Shock, Hemorrhagic,
pubmed-meshheading:18404056-Survival Analysis,
pubmed-meshheading:18404056-Swine,
pubmed-meshheading:18404056-Time Factors,
pubmed-meshheading:18404056-Wounds, Penetrating
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pubmed:year |
2008
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pubmed:articleTitle |
Putting life on hold-for how long? Profound hypothermic cardiopulmonary bypass in a Swine model of complex vascular injuries.
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pubmed:affiliation |
Division of Trauma, Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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