Linked Life Data

18403996

Source:http://linkedlifedata.com/resource/pubmed/id/18403996

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2008-4-11
pubmed:abstractText
With the growing prevalence of obesity, scientific interest in the biology of adipose tissue has been extended to the secretory products of adipocytes, since they have been shown increasingly to affect several aspects of the pathogenesis of obesity-related diseases. Until relatively recently, the role of adipose tissue itself in the development of obesity and its consequences was considered to be a passive one. It is now clear that, in addition to storing energy in the form of triglycerides, adipocytes also secrete a large variety of proteins, including cytokines, chemokines and hormone-like factors. This production of proatherogenic chemokines by adipose tissue is of particular interest, since their local secretion, for example by perivascular adipose depots, may provide a novel mechanistic link between obesity and associated vascular complications.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1558-2027
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
450-60
pubmed:dateRevised
2009-5-28
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
The role of adiposity as a determinant of an inflammatory milieu.
pubmed:affiliation
Division of Cardiology, Department of Cardiothoracic Sciences, Second University of Naples, A O Monaldi, Naples, Italy. paolo.calabro@unina2.it
pubmed:publicationType
Journal Article, Review