rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2008-5-9
|
pubmed:abstractText |
Antibodies against type II collagen (anti-CII) are arthritogenic and central to the initiation of the disease. An animal model of collagen type II-specific monoclonal antibody-induced arthritis (CAIA) has been used for the evaluation of various therapeutic effects in rheumatoid arthritis (RA). We aimed to measure the expression of matrix metalloproteinase (MMP)-9 (gelatinase B), tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) in the acute and chronic stages of the CAIA model for application as a therapeutic marker.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0929-6646
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
107
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
245-52
|
pubmed:meshHeading |
pubmed-meshheading:18400610-Acute Disease,
pubmed-meshheading:18400610-Animals,
pubmed-meshheading:18400610-Arthritis, Experimental,
pubmed-meshheading:18400610-Biological Markers,
pubmed-meshheading:18400610-Chronic Disease,
pubmed-meshheading:18400610-Collagen Type II,
pubmed-meshheading:18400610-Interleukin-1beta,
pubmed-meshheading:18400610-Male,
pubmed-meshheading:18400610-Matrix Metalloproteinase 9,
pubmed-meshheading:18400610-Mice,
pubmed-meshheading:18400610-Mice, Inbred BALB C,
pubmed-meshheading:18400610-RNA, Messenger
|
pubmed:year |
2008
|
pubmed:articleTitle |
MMP-9 mRNA as a therapeutic marker in acute and chronic stages of arthritis induced by type II collagen antibody.
|
pubmed:affiliation |
Hsin Chu General Hospital, Department of Health, Executive Yuan, Taiwan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|