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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1992-5-28
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pubmed:abstractText |
Teicoplanin, a new glycopeptide antibiotic similar to vancomycin, was evaluated in treating 36 hospitalized patients suffering from various Gram-positive infections. The 36 patients received teicoplanin once daily as a mean intravenous injection of 550 mg/day (range 200-800 mg/day). Previous antimicrobial therapy was used in 28% of patients. The mean duration of therapy was 7.5 days (range 3-38 days). The overall clinical success rate was 94%. 24/36 patients (66%) had positive microbiology. Elimination of the pathogens was seen in 75% of all evaluable cases. Four patients with early prosthetic valve endocarditis due to coagulase negative Staphylococcus (3 patients) and Propionibacterium acnes (1 patient) had a favorable clinical and microbiological outcome. No adverse drug reactions were observed. Teicoplanin is safe and effective in the therapy of many different infections caused by Gram-positive bacteria.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1120-009X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
3
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
315-20
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pubmed:dateRevised |
2009-8-4
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pubmed:meshHeading |
pubmed-meshheading:1839742-Adult,
pubmed-meshheading:1839742-Aged,
pubmed-meshheading:1839742-Aged, 80 and over,
pubmed-meshheading:1839742-Drug Resistance, Microbial,
pubmed-meshheading:1839742-Female,
pubmed-meshheading:1839742-Glycopeptides,
pubmed-meshheading:1839742-Gram-Positive Bacteria,
pubmed-meshheading:1839742-Gram-Positive Bacterial Infections,
pubmed-meshheading:1839742-Humans,
pubmed-meshheading:1839742-Injections, Intravenous,
pubmed-meshheading:1839742-Male,
pubmed-meshheading:1839742-Microbial Sensitivity Tests,
pubmed-meshheading:1839742-Middle Aged,
pubmed-meshheading:1839742-Teicoplanin
|
pubmed:year |
1991
|
pubmed:articleTitle |
An open study of teicoplanin in the treatment of gram-positive infections.
|
pubmed:affiliation |
Infection Unit, City Hospital, Aberdeen, Scotland UK.
|
pubmed:publicationType |
Journal Article,
Clinical Trial
|