Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-9-15
pubmed:abstractText
Increasing demand for a flexible catheter tip exists in the rapidly growing fields of vascular and interventional radiology. This article describes a fabrication technology producing a catheter tip with gradually graded or gradient flexibility. Based on deflection mechanics of a tubular construct, three models were incorporated into structural designs. The models included graded wall thickness, tapered shape, or graded Young's moduli. Electrospinning using elastomeric polymer [poly(L-lactide-co-epsilon-caprolactone), polyurethane] solutions on a transversely and rotationally moving mandrel enabled preparation of three prototype tubular tips by either regio-specific control of wall thickness, tapered mandrel, or regiospecific deposition of polyurethanes with different Young's moduli. All prototype tips exhibited high flexibility at tip ends, as verified using a bifurcated vessel model.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1552-4981
pubmed:author
pubmed:copyrightInfo
(c) 2008 Wiley Periodicals, Inc.
pubmed:issnType
Electronic
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
35-41
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Electrospinning fabrication of high-trackable catheter tip with gradually graded or gradient flexibility.
pubmed:affiliation
Genome Biotechnology Laboratory, Kanazawa Institute of Technology, 3-1 Yatsukaho, Hakusan, Ishikawa 924-0838, Japan. tmatsuda@neptune.kanazawa-it.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't