Source:http://linkedlifedata.com/resource/pubmed/id/18390394
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2008-4-8
|
pubmed:abstractText |
Ketamine has been shown to induce rat cytochrome P-450 in a way similar to phenobarbital. However, whether ketamine is able to induce glutathione S-transferase (GST) and UDP-glucuronosyltransferase (UGT), two major phase II drug-metabolizing enzymes, remains unclear. The present study aimed to investigate the effect of ketamine on GST and UGT activities in rats.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1875-4597
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
46
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2-7
|
pubmed:meshHeading |
pubmed-meshheading:18390394-Animals,
pubmed-meshheading:18390394-Dose-Response Relationship, Drug,
pubmed-meshheading:18390394-Enzyme Induction,
pubmed-meshheading:18390394-Glucuronosyltransferase,
pubmed-meshheading:18390394-Glutathione Transferase,
pubmed-meshheading:18390394-Ketamine,
pubmed-meshheading:18390394-Liver,
pubmed-meshheading:18390394-Male,
pubmed-meshheading:18390394-Rats,
pubmed-meshheading:18390394-Rats, Wistar
|
pubmed:year |
2008
|
pubmed:articleTitle |
Induction of hepatic glutathione S-transferase and UDP-glucuronosyltransferase activities by ketamine in rats.
|
pubmed:affiliation |
Department of Anesthesiology, National Taiwan University Hospital, 1 Jen Ai Road, Taipei, Taiwan, R.O.C.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|