Source:http://linkedlifedata.com/resource/pubmed/id/18388068
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
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| pubmed:dateCreated |
2008-6-11
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| pubmed:abstractText |
We investigated the association of apolipoproteins AI and B in relation to the prevalence of metabolic syndrome in a random sample of cardiovascular disease- free adults from the ATTICA study (1,514 men, aged 18-87 y; 1,528 women, aged 18-89 y). Metabolic syndrome was defined according to the National Cholesterol Education Program Adult Treatment Panel III criteria. The prevalence of metabolic syndrome was 25% in men and 15% in women (P < .001). Using the area under the Receiver Operation Characteristic curve, apolipoprotein B/AI was the best diagnostic marker of metabolic syndrome, the optimal discriminating cut-off value of this ratio was 0.72 (sensitivity 74%, specificity 67%), and individuals with apolipoprotein B/AI ratio greater than 0.74 had 3.29 times higher odds of having metabolic syndrome (95% confidence interval: 2.56-4.21) after adjusting for potential confounders.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
1940-1574
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
59
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
335-41
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| pubmed:meshHeading |
pubmed-meshheading:18388068-Adult,
pubmed-meshheading:18388068-Aged,
pubmed-meshheading:18388068-Aged, 80 and over,
pubmed-meshheading:18388068-Apolipoprotein A-I,
pubmed-meshheading:18388068-Apolipoproteins B,
pubmed-meshheading:18388068-Biological Markers,
pubmed-meshheading:18388068-Cross-Sectional Studies,
pubmed-meshheading:18388068-Female,
pubmed-meshheading:18388068-Greece,
pubmed-meshheading:18388068-Humans,
pubmed-meshheading:18388068-Male,
pubmed-meshheading:18388068-Metabolic Syndrome X,
pubmed-meshheading:18388068-Middle Aged,
pubmed-meshheading:18388068-Odds Ratio,
pubmed-meshheading:18388068-Predictive Value of Tests,
pubmed-meshheading:18388068-Prevalence,
pubmed-meshheading:18388068-ROC Curve,
pubmed-meshheading:18388068-Research Design,
pubmed-meshheading:18388068-Risk Assessment,
pubmed-meshheading:18388068-Risk Factors,
pubmed-meshheading:18388068-Sensitivity and Specificity
|
| pubmed:articleTitle |
Risk stratification of apolipoprotein B, apolipoprotein A1, and apolipoprotein B/AI ratio on the prevalence of the metabolic syndrome: the ATTICA study.
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| pubmed:affiliation |
First Cardiology Clinic, School of Medicine, University of Athens, Greece.
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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