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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2008-4-3
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pubmed:abstractText |
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute-onset mucocutaneous diseases induced by infectious agents and/or inciting drugs. Although the pathobiological mechanisms underlying the onset of SJS/TEN have not been fully established, the extreme rarity of cutaneous and ocular surface reactions to drug therapies led us to suspect individual susceptibility. Our previous study of polymorphisms in the HLA-class I genes of 40 Japanese SJS/TEN patients with ocular surface complications showed that in the Japanese, HLA-A*0206 was strongly associated with SJS/TEN. In this study, we investigated the association between HLA class II antigens in addition to HLA class I antigens and SJS/TEN.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-10999875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-11790164,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-12164739,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-15057820,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-17258541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-17314152,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-17475335,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-17900677,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-2404462,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-3477129,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-7115173,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-7375977,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-7477195,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-7741540,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-8466217,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-8841298,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-9098260,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18385790-9211745
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1090-0535
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
550-5
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18385790-Adult,
pubmed-meshheading:18385790-Alleles,
pubmed-meshheading:18385790-Asian Continental Ancestry Group,
pubmed-meshheading:18385790-Eye Diseases,
pubmed-meshheading:18385790-Female,
pubmed-meshheading:18385790-HLA-A Antigens,
pubmed-meshheading:18385790-HLA-A1 Antigen,
pubmed-meshheading:18385790-HLA-A2 Antigen,
pubmed-meshheading:18385790-HLA-DQ Antigens,
pubmed-meshheading:18385790-HLA-DQ beta-Chains,
pubmed-meshheading:18385790-Histocompatibility Antigens Class I,
pubmed-meshheading:18385790-Histocompatibility Antigens Class II,
pubmed-meshheading:18385790-Humans,
pubmed-meshheading:18385790-Male,
pubmed-meshheading:18385790-Middle Aged,
pubmed-meshheading:18385790-Stevens-Johnson Syndrome
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pubmed:year |
2008
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pubmed:articleTitle |
HLA class I and II gene polymorphisms in Stevens-Johnson syndrome with ocular complications in Japanese.
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pubmed:affiliation |
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan. mueta@ophth.kpu-m.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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