|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0011306,
umls-concept:C0015392,
umls-concept:C0024432,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0035331,
umls-concept:C0042160,
umls-concept:C0206116,
umls-concept:C0271510,
umls-concept:C0851827,
umls-concept:C1439296,
umls-concept:C1701901,
umls-concept:C1704711
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2008-4-3
|
|
pubmed:abstractText |
The chemokine receptor CX3CR1 is expressed by monocyte-derived dendritic cells (DCs) and macrophages. CX3CR1 mediates leukocyte migration and adhesion in homeostatic and inflammatory conditions. Mice lacking Cx3cr1 have altered distribution and function of DC subpopulations in some tissue microenvironments. The present study compares the distribution of monocyte-derived cells in the normal retina and uveal tract as a prelude to the investigation of the role of CX3CR1 in murine models of ocular disease.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0146-0404
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
49
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1599-608
|
|
pubmed:meshHeading |
pubmed-meshheading:18385080-Animals,
pubmed-meshheading:18385080-Antigens, CD,
pubmed-meshheading:18385080-Cell Count,
pubmed-meshheading:18385080-Cell Movement,
pubmed-meshheading:18385080-Dendritic Cells,
pubmed-meshheading:18385080-Female,
pubmed-meshheading:18385080-Flow Cytometry,
pubmed-meshheading:18385080-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:18385080-Gene Expression,
pubmed-meshheading:18385080-Green Fluorescent Proteins,
pubmed-meshheading:18385080-Immunophenotyping,
pubmed-meshheading:18385080-Macrophages,
pubmed-meshheading:18385080-Mice,
pubmed-meshheading:18385080-Mice, Inbred BALB C,
pubmed-meshheading:18385080-Mice, Inbred C57BL,
pubmed-meshheading:18385080-Mice, Transgenic,
pubmed-meshheading:18385080-Microglia,
pubmed-meshheading:18385080-Microscopy, Confocal,
pubmed-meshheading:18385080-Receptors, Chemokine,
pubmed-meshheading:18385080-Retina,
pubmed-meshheading:18385080-Uvea
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Retinal microglia and uveal tract dendritic cells and macrophages are not CX3CR1 dependent in their recruitment and distribution in the young mouse eye.
|
|
pubmed:affiliation |
School of Anatomy and Human Biology, The University of Western Australia, Crawley, Western Australia.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
