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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1A
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pubmed:dateCreated |
2008-4-3
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pubmed:abstractText |
MicroRNAs (miRNAs) are approximately 22 nucleotide long, non-coding RNAs that regulate gene expression by binding to the 3'-untranslated region of target mRNAs and also a variety of cellular processes. It has recently been established that dysregulation of miRNA expression can be detected in the majority of human cancers. A variety of high-throughput screening methods has been developed to identify dysregulated miRNA species in tumours. For retrospective clinical studies formalin-fixed, paraffin-embedded (FFPE) tissue is the most widely used material.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
119-23
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pubmed:meshHeading |
pubmed-meshheading:18383833-Base Sequence,
pubmed-meshheading:18383833-Formaldehyde,
pubmed-meshheading:18383833-Frozen Sections,
pubmed-meshheading:18383833-Gene Expression Profiling,
pubmed-meshheading:18383833-Humans,
pubmed-meshheading:18383833-Liver Neoplasms,
pubmed-meshheading:18383833-MicroRNAs,
pubmed-meshheading:18383833-Molecular Sequence Data,
pubmed-meshheading:18383833-Polymerase Chain Reaction,
pubmed-meshheading:18383833-Retrospective Studies,
pubmed-meshheading:18383833-Tissue Fixation,
pubmed-meshheading:18383833-Tonsillar Neoplasms
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pubmed:articleTitle |
Unlocking pathology archives for microRNA-profiling.
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pubmed:affiliation |
Institute for Pathology, UKSH Campus Luebeck, Luebeck, Germany.
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pubmed:publicationType |
Journal Article
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