| pubmed-article:1838201 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1838201 | lifeskim:mentions | umls-concept:C0599779 | lld:lifeskim |
| pubmed-article:1838201 | lifeskim:mentions | umls-concept:C0003289 | lld:lifeskim |
| pubmed-article:1838201 | lifeskim:mentions | umls-concept:C0011570 | lld:lifeskim |
| pubmed-article:1838201 | lifeskim:mentions | umls-concept:C0242702 | lld:lifeskim |
| pubmed-article:1838201 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
| pubmed-article:1838201 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1838201 | pubmed:dateCreated | 1992-3-9 | lld:pubmed |
| pubmed-article:1838201 | pubmed:abstractText | Rats subjected chronically (12 weeks) to a variety of mild, unpredictable stressors showed a reduced consumption of sucrose or a sucrose/saccharin mixture in two-bottle consumption tests (sweet solution versus water). The deficit was apparent within 2 weeks of stress; normal behaviour was restored by chronic (7 weeks) treatment with the tricyclic antidepressants desmethylimipramine (DMI) or amitriptyline (AMI). Acute administration of the dopamine D1 receptor antagonist SCH-23390 1 week after withdrawal, or the dopamine D2 receptor antagonist sulpiride 2 weeks after withdrawal, were without effect in vehicle-treated stressed animals, and in non-stressed animals. However, the DA antagonists selectively reversed the improvement of performance in DMI- or AMI-treated stressed animals. This suggests that an increase in functional activity at DA synapses is the mechanism of action of DMI and AMI in this model. | lld:pubmed |
| pubmed-article:1838201 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1838201 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1838201 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1838201 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1838201 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1838201 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1838201 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1838201 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1838201 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1838201 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1838201 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1838201 | pubmed:issn | 0033-3158 | lld:pubmed |
| pubmed-article:1838201 | pubmed:author | pubmed-author:SampsonDD | lld:pubmed |
| pubmed-article:1838201 | pubmed:author | pubmed-author:WillnerPP | lld:pubmed |
| pubmed-article:1838201 | pubmed:author | pubmed-author:MuscatRR | lld:pubmed |
| pubmed-article:1838201 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1838201 | pubmed:volume | 104 | lld:pubmed |
| pubmed-article:1838201 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1838201 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1838201 | pubmed:pagination | 491-5 | lld:pubmed |
| pubmed-article:1838201 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:1838201 | pubmed:meshHeading | pubmed-meshheading:1838201-... | lld:pubmed |
| pubmed-article:1838201 | pubmed:meshHeading | pubmed-meshheading:1838201-... | lld:pubmed |
| pubmed-article:1838201 | pubmed:meshHeading | pubmed-meshheading:1838201-... | lld:pubmed |
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| pubmed-article:1838201 | pubmed:meshHeading | pubmed-meshheading:1838201-... | lld:pubmed |
| pubmed-article:1838201 | pubmed:meshHeading | pubmed-meshheading:1838201-... | lld:pubmed |
| pubmed-article:1838201 | pubmed:meshHeading | pubmed-meshheading:1838201-... | lld:pubmed |
| pubmed-article:1838201 | pubmed:meshHeading | pubmed-meshheading:1838201-... | lld:pubmed |
| pubmed-article:1838201 | pubmed:meshHeading | pubmed-meshheading:1838201-... | lld:pubmed |
| pubmed-article:1838201 | pubmed:meshHeading | pubmed-meshheading:1838201-... | lld:pubmed |
| pubmed-article:1838201 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1838201 | pubmed:articleTitle | Reversal of antidepressant action by dopamine antagonists in an animal model of depression. | lld:pubmed |
| pubmed-article:1838201 | pubmed:affiliation | Psychology Department, City of London Polytechnic, UK. | lld:pubmed |
| pubmed-article:1838201 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1838201 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1838201 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1838201 | lld:pubmed |
