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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-4-2
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pubmed:abstractText |
Cyclooxygenase-2 (COX-2)-specific inhibition suppresses carcinogenesis in preclinical models and is a promising strategy for preventing oral cancer. In this pilot randomized phase II study, we evaluated the efficacy and safety of the COX-2 inhibitor celecoxib in patients with oral premalignant lesions (OPL).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AtwellAntheaA,
pubmed-author:BoyleJay OJO,
pubmed-author:DannenbergAndrew JAJ,
pubmed-author:DeysSS,
pubmed-author:DuBaohengB,
pubmed-author:El-NaggarAdel KAK,
pubmed-author:HelmanJoseph IJI,
pubmed-author:LeeJ JackJJ,
pubmed-author:LippmanScott MSM,
pubmed-author:NathanCherie-AnnCO,
pubmed-author:OndreyFrank GFG,
pubmed-author:PapadimitrakopoulouVassiliki AVA,
pubmed-author:PetersonDouglas EDE,
pubmed-author:WilliamWilliam NWNJr,
pubmed-author:YuehBevanB
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2095-101
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pubmed:dateRevised |
2009-10-28
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pubmed:meshHeading |
pubmed-meshheading:18381950-Adult,
pubmed-meshheading:18381950-Aged,
pubmed-meshheading:18381950-Aged, 80 and over,
pubmed-meshheading:18381950-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:18381950-Cyclooxygenase 2,
pubmed-meshheading:18381950-Cyclooxygenase 2 Inhibitors,
pubmed-meshheading:18381950-Female,
pubmed-meshheading:18381950-Humans,
pubmed-meshheading:18381950-Hyperplasia,
pubmed-meshheading:18381950-Male,
pubmed-meshheading:18381950-Middle Aged,
pubmed-meshheading:18381950-Mouth Neoplasms,
pubmed-meshheading:18381950-Pilot Projects,
pubmed-meshheading:18381950-Placebos,
pubmed-meshheading:18381950-Polymerase Chain Reaction,
pubmed-meshheading:18381950-Precancerous Conditions,
pubmed-meshheading:18381950-Pyrazoles,
pubmed-meshheading:18381950-RNA, Messenger,
pubmed-meshheading:18381950-Sulfonamides
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pubmed:year |
2008
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pubmed:articleTitle |
Pilot randomized phase II study of celecoxib in oral premalignant lesions.
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pubmed:affiliation |
Department of Thoracic/Head, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. vpapadim@mdanderson.org
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II
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