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pubmed:abstractText |
To examine the hypothesis that young adults with major depressive disorder (MDD) would show increased affective bias to painful and nonpainful experimental heat stimuli, as evidenced by an increased responsiveness to warm and hot temperatures. Pain and depression often occur together. Pain is both a sensation and an affective experience. Similarly, depression is associated frequently with somatic symptoms as well as emotional dysphoria. Existing evidence indicates that MDD may be associated with altered pain processing. However, the extent to which alterations in experimentally controlled heat pain sensations are related to increased affective bias in MDD is unknown.
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pubmed:affiliation |
Department of Psychiatry, Laboratory of Biological Dynamics and Theoretical Medicine, University of California, San Diego, 8950 Villa La Jolla Dr., Suite C213, La Jolla, CA 92037-0985, USA. istrigo@ucsd.edu.
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