Linked Life Data

18378367

Source:http://linkedlifedata.com/resource/pubmed/id/18378367

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
17
pubmed:dateCreated
2008-4-11
pubmed:abstractText
Polio eradication programme was launched in India in 1995, and polio eradication was expected to occur by 2000. Remarkable decline in polio incidence occurred, but, polio was not eradicated. Majority of polio cases are occurring in two states viz., Uttar Pradesh and Bihar. It is also being observed that majority of polio cases had received many doses of polio vaccine. In 2005 monovalent OPV1 (mOPV1) and monovalent OPV3 (mOPV3) were also introduced in Uttar Pradesh and Bihar, but, number of polio cases increased 10-fold in 2006. In 2007 number of vaccination rounds were increased to one round every month, but in 2007 number of polio cases increased further. In 2005 there were 66 polio cases whereas in 2006 and 2007 number of polio cases increased to 676 and 863, respectively. Some genetic factors in children from Uttar Pradesh and Bihar appear to be responsible for poor antibody generation by OPV. Some mutations in polio viruses may be responsible for development of resistance to antibodies generated by OPV and a reason for the recent steep rise in polio incidence since 2006. Because of these two factors, OPV cannot eradicate polio from India.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0264-410X
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2058-61
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
OPV cannot eradicate polio from India: do we need any further evidence?
pubmed:affiliation
Maharaja Agrasen Hospital, Paediatrics, Vidhyadhar Nagar, Jaipur, Rajasthan 302023, India. dryashpaul2003@yahoo.com
pubmed:publicationType
Journal Article