Linked Life Data

18377788

Source:http://linkedlifedata.com/resource/pubmed/id/18377788

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2008-4-1
pubmed:abstractText
Postprandial hyperglycemia is increasingly recognized as an independent risk factor for cardiovascular disease. Glycemic "spikes" may adversely affect vascular structure and function via multiple mechanisms, including (acutely and/or chronically) oxidative stress, inflammation, low-density lipoprotein oxidation, protein glycation, and procoagulant activity. Postprandial glycemia can be reliably predicted by considering both the amount and type of carbohydrate. In particular, the glycemic index (GI), a measure of postprandial glycemic potency weight for weight of carbohydrate, has provided insights that knowledge of the sugar or starch content has not. In prospective observational studies, dietary GI and/or glycemic load independently predict cardiovascular disease, with relative risk ratios of 1.2 to 1.7 comparing highest and lowest quintiles. In randomized controlled trials in overweight subjects, diets based on low-GI carbohydrates have produced better cardiovascular-related outcomes than conventional low-fat diets. Taken together, the findings suggest that health professionals may be able to improve cardiovascular outcomes by recommending the judicious use of low- GI/glycemic load foods.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1534-6242
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
479-85
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
The glycemic index and cardiovascular disease risk.
pubmed:affiliation
Human Nutrition Unit (G08), University of Sydney, Camperdown, NSW, 2006, Australia. j.brandmiller@mmb.usyd.edu.au
pubmed:publicationType
Journal Article, Review