Source:http://linkedlifedata.com/resource/pubmed/id/18376259
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2008-3-31
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pubmed:abstractText |
We carried out a cross-sectional study of 115 healthy infants, younger than 6 months old, exclusively breast-fed or formula-fed, to investigate correlations between circulating leptin concentrations and body composition measurements. Serum leptin was evaluated with radioimmunoassay, and body composition with bioelectrical impedance analysis. Multiple regression analysis showed a relationship between serum leptin and body mass index in the entire study population (P = 0.042). There was a significant negative relationship between serum leptin and phase angle (P = 0.006) in formula-fed infants. Serum leptin was positively related to subscapular skinfold thickness (P = 0.055) and negatively to reactance (P = 0.057) only in formula-fed infants, although the differences were just below significance. Serum leptin concentration was higher in breast-fed infants (P = 0.002), and was not correlated with body composition parameters. This study indicates that there is a relation between leptin and infant body composition in the first months of life, although the link needs to be explored further.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1536-4801
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
348-51
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pubmed:meshHeading |
pubmed-meshheading:18376259-Body Composition,
pubmed-meshheading:18376259-Body Mass Index,
pubmed-meshheading:18376259-Child Development,
pubmed-meshheading:18376259-Cross-Sectional Studies,
pubmed-meshheading:18376259-Electric Impedance,
pubmed-meshheading:18376259-Female,
pubmed-meshheading:18376259-Humans,
pubmed-meshheading:18376259-Infant,
pubmed-meshheading:18376259-Infant, Newborn,
pubmed-meshheading:18376259-Infant Food,
pubmed-meshheading:18376259-Infant Formula,
pubmed-meshheading:18376259-Leptin,
pubmed-meshheading:18376259-Male,
pubmed-meshheading:18376259-Milk, Human,
pubmed-meshheading:18376259-Skinfold Thickness
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pubmed:year |
2008
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pubmed:articleTitle |
Looking for a relation between serum leptin concentration and body composition parameters in healthy term infants in the first 6 months of life.
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pubmed:affiliation |
Department of Pediatrics, Regina Margherita Children's Hospital, University of Turin, Italy. francesco.savino@unito.it
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pubmed:publicationType |
Journal Article
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