|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0004048,
umls-concept:C0008976,
umls-concept:C0021289,
umls-concept:C0021294,
umls-concept:C0028128,
umls-concept:C0035203,
umls-concept:C0042491,
umls-concept:C0183683,
umls-concept:C0205082,
umls-concept:C0344211,
umls-concept:C0439234,
umls-concept:C0728731,
umls-concept:C1145670,
umls-concept:C1171411,
umls-concept:C1317973,
umls-concept:C1521721,
umls-concept:C1522577,
umls-concept:C2587213
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|
pubmed:issue |
6
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|
pubmed:dateCreated |
2008-10-22
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|
pubmed:abstractText |
Trials of inhaled nitric oxide (iNO) used short term in preterm infants with severe respiratory failure have to date shown no evidence of benefit, and there have been no trials reporting follow-up to 4 years of age. The INNOVO trial recruited 108 infants (55 iNO arm and 53 controls) from 15 neonatal units. By 1 year of age 59% had died, and 84% of the survivors had signs of impairment or disability.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Nov
|
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pubmed:issn |
1468-2052
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|
pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
93
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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|
pubmed:pagination |
F430-5
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pubmed:meshHeading |
pubmed-meshheading:18375612-Administration, Inhalation,
pubmed-meshheading:18375612-Bronchodilator Agents,
pubmed-meshheading:18375612-Combined Modality Therapy,
pubmed-meshheading:18375612-Developmental Disabilities,
pubmed-meshheading:18375612-Disability Evaluation,
pubmed-meshheading:18375612-Follow-Up Studies,
pubmed-meshheading:18375612-Health Care Costs,
pubmed-meshheading:18375612-Humans,
pubmed-meshheading:18375612-Infant, Newborn,
pubmed-meshheading:18375612-Infant, Premature,
pubmed-meshheading:18375612-Infant, Premature, Diseases,
pubmed-meshheading:18375612-Nitric Oxide,
pubmed-meshheading:18375612-Respiration, Artificial,
pubmed-meshheading:18375612-Respiratory Insufficiency,
pubmed-meshheading:18375612-Treatment Outcome
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|
pubmed:year |
2008
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|
pubmed:articleTitle |
The INNOVO multicentre randomised controlled trial: neonatal ventilation with inhaled nitric oxide versus ventilatory support without nitric oxide for severe respiratory failure in preterm infants: follow up at 4-5 years.
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|
pubmed:affiliation |
Neonatal Unit, Leicester Royal Infirmary, Leicester, UK. huddy@doctors.org.uk
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|
