Source:http://linkedlifedata.com/resource/pubmed/id/18375254
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2008-3-31
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pubmed:abstractText |
Acute rejection (AR) and hepatitis B virus (HBV) recurrence after liver transplantation (LT) are the two major complications leading to chronic graft dysfunction. Genomic polymorphisms in interleukin (IL)-10, tumor necrosis factor (TNF)alpha and transforming growth factor (TGF)beta1 genes have been found to affect the susceptibility to certain diseases. However, the relationship between cytokine gene polymorphisms and risk of AR as well as HBV recurrence after LT in Han Chinese has not been reported. The objective of the present study was to investigate the association of polymorphisms within these cytokine genes with the risk of AR as well as HBV recurrence.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0188-4409
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
420-8
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pubmed:meshHeading |
pubmed-meshheading:18375254-Asian Continental Ancestry Group,
pubmed-meshheading:18375254-Cytokines,
pubmed-meshheading:18375254-Gene Frequency,
pubmed-meshheading:18375254-Genetic Predisposition to Disease,
pubmed-meshheading:18375254-Graft Rejection,
pubmed-meshheading:18375254-Haplotypes,
pubmed-meshheading:18375254-Hepatitis B,
pubmed-meshheading:18375254-Humans,
pubmed-meshheading:18375254-Interleukin-10,
pubmed-meshheading:18375254-Liver Transplantation,
pubmed-meshheading:18375254-Polymorphism, Single Nucleotide,
pubmed-meshheading:18375254-Recurrence,
pubmed-meshheading:18375254-Transforming Growth Factor beta1,
pubmed-meshheading:18375254-Tumor Necrosis Factor-alpha
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pubmed:year |
2008
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pubmed:articleTitle |
Polymorphisms in cytokine genes and their association with acute rejection and recurrence of hepatitis B in Chinese liver transplant recipients.
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pubmed:affiliation |
Department of Hepatobiliary Pancreatic Surgery, Key Laboratory of Multiple Organ Transplantation, Ministry of Public Health, First Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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