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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1992-2-18
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pubmed:abstractText |
Two cases of acute megakaryoblastic leukemia in a 4 month-old and a 13 year-old girl are described. In the first case who presented with a large hepatomegaly and portal fibrosis, the diagnosis was made from the surface phenotyping of megakaryoblasts; a trisomy 13, 14 and 19 and an extra chromosome X were present in the bone marrow. An electron microscopy study of megakaryoblasts was necessary to identify the second case. Both children died shortly after treatment (cytosine-arabinoside at low dosage in the first case and polychemotherapy in the second). The 51 other cases reported in the literature are reviewed.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
|
pubmed:month |
Oct
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pubmed:issn |
0003-9764
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
48
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
563-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1837448-Adolescent,
pubmed-meshheading:1837448-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:1837448-Chromosome Aberrations,
pubmed-meshheading:1837448-Chromosome Disorders,
pubmed-meshheading:1837448-Down Syndrome,
pubmed-meshheading:1837448-Female,
pubmed-meshheading:1837448-Hepatomegaly,
pubmed-meshheading:1837448-Humans,
pubmed-meshheading:1837448-Infant,
pubmed-meshheading:1837448-Karyotyping,
pubmed-meshheading:1837448-Leukemia, Megakaryoblastic, Acute
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pubmed:year |
1991
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pubmed:articleTitle |
[Acute megakaryoblastic leukemia. Relation to trisomy 21].
|
pubmed:affiliation |
Service de Pédiatrie, CHRU et du Laboratoire d'Anatomo-Pathologie, Caen.
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pubmed:publicationType |
Journal Article,
English Abstract,
Review,
Case Reports
|