Linked Life Data

18369652

Source:http://linkedlifedata.com/resource/pubmed/id/18369652

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-12-16
pubmed:abstractText
The Leser-Trelat sign is defined as the association of multiple, eruptive seborrheic keratoses with an internal malignancy of a usually advanced stage. We report the case of malignant melanoma in an 82-year-old man covered with hundreds of greyish-dark seborrheic keratoses resembling a Christmas tree pattern, who was diagnosed with metastasized malignant melanoma involving the parotid gland and lymph nodes. Though the pathogenesis of Leser-Trelat sign is still unknown, spontaneous regression of the seborrheic keratoses following tumor reduction described in some cases argues for a paraneoplastic origin of this highly instructive clinical entity. Physicians should consider a workup for internal malignancy in patients presenting with multiple eruptive seborrheic keratoses.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1434-4726
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
266
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
297-9
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Leser-Trelat sign in metastasized malignant melanoma.
pubmed:affiliation
Department of Otorhinolaryngology, Ludwig-Maximilian University, Marchioninistr. 15, 81377 Munich, Germany. vanessa.siedek@med.uni-muenchen.de
pubmed:publicationType
Journal Article, Case Reports