rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2008-12-1
|
pubmed:abstractText |
Here we report a rare case of primary T-cell lymphoma of the thyroid gland. A 32-year-old Chinese man was admitted to our hospital because of marked goiter and subcutaneous nodules. Computed tomography (CT) scan of the neck disclosed diffuse enlargement of the thyroid gland. A diagnosis of peripheral T-cell lymphoma was made according to cytopathological findings of fine-needle aspiration (FNA) of the thyroid gland and skin biopsy. Immunohistochemistry stain showed that the tumor was positive for CD3 and negative for CD20. Clonal T-cell receptor (TCR-gamma) gene rearrangements were demonstrated by polymerase chain reaction. After six cycles of combination chemotherapy (bleomycin, cyclophosphamide, doxorubicin, vincristine, and prednisone), the thyroid retracted to normal size gradually.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1357-0560
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
25
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
462-6
|
pubmed:meshHeading |
pubmed-meshheading:18363111-Adult,
pubmed-meshheading:18363111-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:18363111-Bleomycin,
pubmed-meshheading:18363111-Cyclophosphamide,
pubmed-meshheading:18363111-Doxorubicin,
pubmed-meshheading:18363111-Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor,
pubmed-meshheading:18363111-Humans,
pubmed-meshheading:18363111-Immunohistochemistry,
pubmed-meshheading:18363111-Lymphoma, T-Cell,
pubmed-meshheading:18363111-Male,
pubmed-meshheading:18363111-Polymerase Chain Reaction,
pubmed-meshheading:18363111-Prednisone,
pubmed-meshheading:18363111-Thyroid Neoplasms,
pubmed-meshheading:18363111-Tomography, X-Ray Computed,
pubmed-meshheading:18363111-Vincristine
|
pubmed:year |
2008
|
pubmed:articleTitle |
Primary T-cell lymphoma of the thyroid: case report and review of the literature.
|
pubmed:affiliation |
Department of Endocrinology and Metabolism, Peking Union Medical College Hospital, Shuai Fu Yuan 1#, DongCheng District, Beijing, 100730, P.R. China.
|
pubmed:publicationType |
Journal Article,
Case Reports
|