Linked Life Data

18362081

Source:http://linkedlifedata.com/resource/pubmed/id/18362081

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-5-27
pubmed:abstractText
Electron paramagnetic resonance (EPR)-based oximetry is capable of quantifying oxygen content in samples. However, for a heterogeneous environment with multiple pO2 values, peak-to-peak linewidth of the composite EPR lineshape does not provide a reliable estimate of the overall pO2 in the sample. The estimate, depending on the heterogeneity, can be severely biased towards narrow components. To address this issue, we suggest a postprocessing method to recover the linewidth histogram which can be used in estimating meaningful parameters, such as the mean and median pO2 values. This information, although not as comprehensive as obtained by EPR spectral-spatial imaging, goes beyond what can be generally achieved with conventional EPR spectroscopy. Substantially shorter acquisition times, in comparison to EPR imaging, may prompt its use in clinically relevant models. For validation, simulation and EPR experiment data are presented.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/18362081-11567578, http://linkedlifedata.com/resource/pubmed/commentcorrection/18362081-11739316, http://linkedlifedata.com/resource/pubmed/commentcorrection/18362081-14572616, http://linkedlifedata.com/resource/pubmed/commentcorrection/18362081-1663949, http://linkedlifedata.com/resource/pubmed/commentcorrection/18362081-17276111, http://linkedlifedata.com/resource/pubmed/commentcorrection/18362081-3023786, http://linkedlifedata.com/resource/pubmed/commentcorrection/18362081-7809170, http://linkedlifedata.com/resource/pubmed/commentcorrection/18362081-8390665, http://linkedlifedata.com/resource/pubmed/commentcorrection/18362081-9269432, http://linkedlifedata.com/resource/pubmed/commentcorrection/18362081-9632554, http://linkedlifedata.com/resource/pubmed/commentcorrection/18362081-9889898
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1090-7807
pubmed:author
pubmed:issnType
Print
pubmed:volume
192
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
269-74
pubmed:dateRevised
2011-6-8
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Estimation of mean and median pO2 values for a composite EPR spectrum.
pubmed:affiliation
Center for Biomedical EPR Spectroscopy and Imaging, Davis Heart and Lung Research Institute, Department of Internal Medicine, The Ohio State University, 420 West 12th Avenue, TMRF-114, Columbus, OH 43210, USA.
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural